3,7 Corneal deposits may appear within two to three weeks of starting treatment and usually resolve when the Hydroxychloroquine is used widely for the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis, and related inflammatory and dermatologic conditions
HCQ is originally an antimalarial drug but was quickly noted for its anti-inflammatory and immunomodulatory effects and became a cornerstone drug in the
Importance According to evidence-based, expert recommendations, long-term users of chloroquine or hydroxychloroquine sulfate should undergo regular visits to eye care
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Hydroxychloroquine (HCQ) is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as
Medication-related maculopathy – Long-term use of medication that treats rheumatoid arthritis or lupus such as chloroquine or hydroxychloroquine (Plaquenil)
Prophylaxis: (in chloroquine-sensitive regions): 500 mg (300mg base) PO starting one week prior to entry, continue once weekly and then four weeks after leaving
2 This contrasts with the recently updated United Kingdom guidelines, which do not recommend any form of screening in
Browning DJ
Biological techniques
She did not have any history of eye disease and Hydroxychloroquine is used widely for the treatment of systemic lupus erythematosus (SLE), rheumatoid arthritis, and related inflammatory and dermatologic conditions
Hydroxychloroquine is a front-line treatment for systemic lupus erythematosus and other rheumatic diseases, but can cause retinopathy
The antimalarial drug chloroquine, although widely replaced by hydroxychloroquine due to its lower risk of developing retinopathy as a serious ocular complication, is still being used in many countries for the treatment for rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis []
A fourth drug, bevacizumab (Avastin), can be used off-label for the treatment of diabetic macular edema
Additionally, the current detection methods in screening for early recognition of maculopathy and their prognostic significance are reviewed
This case report presents a pictorially well-documented case with multimodal images of a progression of maculopathy despite discontinuation of chloroquine treatment in a long-term follow-up over 6 years
A 53- year-old lady on chloroquine for treatment of rheumatoid arthritis developed decrease in vision 36 months after initiation of the treatment